1-(苄氨基)-3-氯-2-丙醇合成路线 （共 12 条）
反应条件
in Petroleum ether 3 h; Heating / reflux;
参考文献
WO2006/25634 A1, ;
Page/Page column 12 ;
反应条件
triethylamine in dichloromethane T=20°C; 3 h;
参考文献
Journal of Organic Chemistry, , vol. 69, # 8 p. 2703 - 2710
反应条件
1: 89 percent / Et3N / CH2Cl2 / 3 h / 20 °C 2: 71 percent / Et3N / acetonitrile / 48 h / Heating View Scheme
参考文献
Higgins, Robert H.; Eaton, Quentin L.; Worth, Leroy; Peterson, Myra V.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 255 - 259
反应条件
1H-imidazole; acetonitrile; trimethylamine 1) 1.5 h, 2) reflux 3 days; Yield given. Multistep reaction;
参考文献
Higgins, Robert H.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1489 - 1491
反应条件
triethylamine; acetonitrile 72 h; Heating; Yield given;
参考文献
Higgins, Robert H.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1489 - 1491
反应条件
triethylamine acetonitrile, reflux, 3 days; Yield given. Multistep reaction;
参考文献
Higgins, Robert H.; Watson, Monique R.; Faircloth, William J.; Eaton, Quentin L.; Jenkins, Harvey
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 383 - 387
反应条件
1: sodium hydrogencarbonate / acetonitrile / 7 h / 30 °C / Inert atmosphere; Reflux; Large scale reaction 2: hydrogenchloride / dichloromethane / 0.5 h / Large scale reaction View Scheme
参考文献
Krishna Reddy; Udaykiran; Chintamani; Mahesh Reddy; Kameswararao, Ch.; Madhusudhan
Organic Process Research and Development, 2011 , vol. 15, # 2 p. 462 - 466
反应条件
sodium hydrogencarbonate in acetonitrile 7 h; Heating;
参考文献
Isoda, Takeshi; Yamamura, Itsuki; Tamai, Satoshi; Kumagai, Toshio; Nagao, Yoshimitsu
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 10 p. 1408 - 1411
反应条件
1: petroleum ether / 3 h / Heating 2: triethylamine / acetonitrile / 72 h / Heating 3: 77 percent / CH3ONa / methanol / 1 h / Ambient temperature 4: 1.06 g / Py*SO3, Et3N / dimethylsulfoxide / 0.5 h / 40 °C View Scheme
参考文献
Katritzky, Alan R.; Cundy, Darren J.; Chen, Jie
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 2 p. 271 - 276
反应条件
calcium trifluoromethane sulfonate in acetonitrile
T=20°C; 4 h;
参考文献
Cepanec, Ivica; Litvic, Mladen; Mikuldas, Hrvoje; Bartolincic, Anamarija; Vinkovic, Vladimir
Tetrahedron, 2003 , vol. 59, # 14 p. 2435 - 2439
