5-吡啶-4-基环己烷-1,3-二酮合成路线 （共 3 条）
反应条件
1: toluene / 1 h / Heating
2: EtONa / ethanol / 2 h / Heating
3: 10percent aq. NaOH / 2 h / Heating
4: concd H2SO4 / 4 h / Heating
View Scheme
参考文献
Kesten, Stephen J.; Degnan, Margaret J.; Hung, Jocelyn; McNamara, Dennis J.; Ortwine, Daniel F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3429 - 3447
反应条件
1: EtONa / ethanol / 2 h / Heating
2: 10percent aq. NaOH / 2 h / Heating
3: concd H2SO4 / 4 h / Heating
View Scheme
参考文献
Kesten, Stephen J.; Degnan, Margaret J.; Hung, Jocelyn; McNamara, Dennis J.; Ortwine, Daniel F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3429 - 3447
反应条件
1: 10percent aq. NaOH / 2 h / Heating
2: concd H2SO4 / 4 h / Heating
View Scheme
参考文献
Kesten, Stephen J.; Degnan, Margaret J.; Hung, Jocelyn; McNamara, Dennis J.; Ortwine, Daniel F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3429 - 3447
