(1H-吲哚-3-亚甲基)丙二腈合成路线 （共 9 条）
参考文献
Yamashita, Yoshiro; Suzuki, Daisuke; Masumura, Mitsuo
Heterocycles, 1981 , vol. 16, # 9 p. 1499 - 1502
反应条件
triethylamine in ethanol Heating;
参考文献
Abdelrazek, Fathy M.; Metz, Peter; Kataeva, Olga; Jaeger, Anne; El-Mahrouky, Sherif F.
Archiv der Pharmazie, 2007 , vol. 340, # 10 p. 543 - 548
反应条件
triphenylphosphine
Knoevenagel condensation; 0.05 h; microwave irradiation;
参考文献
Yadav, Jhillu S.; Subba Reddy, Basi V.; Basak, Ashok K.; Visali, Boddapati; Narsaiah, Akkirala Venkat; Nagaiah, Kommu
European Journal of Organic Chemistry, 2004 , # 3 p. 546 - 551
反应条件
triethylamine in N,N-dimethyl-formamide
T=80 - 90°C; Knoevenagel Condensation; 0.75 h;
参考文献
Ranise, Angelo; Lucchesini, Francesco; Caviglia, Matteo; Alfei, Silvana; Spallarossa, Andrea; Caneva, Chiara
Tetrahedron, 2013 , vol. 69, # 51 p. 10858 - 10868
反应条件
in ethanol
T=25°C; 0.5 h;
参考文献
Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721
反应条件
acetic anhydride; ytterbium(III) triflate
T=40°C; 1 h;
参考文献
Yu, Chuanming; Zhou, Baocheng; Su, Weike; Xu, Zhenyuan
Synthetic Communications, 2006 , vol. 36, # 22 p. 3447 - 3453
反应条件
sodium hydride in tetrahydrofuran
参考文献
Yamashita, Yoshiro; Suzuki, Daisuke; Masumura, Mitsuo
Heterocycles, 1981 , vol. 16, # 9 p. 1499 - 1502
反应条件
1: benzoyl chloride / 5 - 20 °C
2: triethylamine / N,N-dimethyl-formamide / 0.75 h / 80 - 90 °C
View Scheme
参考文献
Ranise, Angelo; Lucchesini, Francesco; Caviglia, Matteo; Alfei, Silvana; Spallarossa, Andrea; Caneva, Chiara
Tetrahedron, 2013 , vol. 69, # 51 p. 10858 - 10868
反应条件
1: 96 percent / benzene / 2 h / Heating; removing the liberated water
2: 97 percent / ethanol / 0.5 h / 25 °C
View Scheme
参考文献
Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721
