3-(2-吗啉乙氧基)苯硼酸频那醇酯合成路线 （共 4 条）
反应条件
caesium carbonate; potassium iodide in DMF (N,N-dimethyl-formamide)
T=65°C; 12 h;
参考文献
Sugen, Inc.
Patent: US2004/220189 A1, 2004 ;
Location in patent: Page 37 ;
US 20040220189 A1
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in 1,4-dioxane
T=90°C; 16 h; Inert atmosphere;
参考文献
KADMON CORPORATION, LLC; BOXER, Michael; RYAN, John; TONRA, James
Patent: WO2014/55999 A2, 2014 ;
Location in patent: Paragraph 0305 ;
反应条件
1: potassium iodide; potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 16 h / 90 °C / |Inert atmosphere
View Scheme
参考文献
KADMON CORPORATION, LLC; BOXER, Michael; RYAN, John; TONRA, James
Patent: WO2014/55999 A2, 2014 ;
反应条件
1: potassium iodide; potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 16 h / 90 °C / |Inert atmosphere
View Scheme
参考文献
KADMON CORPORATION, LLC; BOXER, Michael; RYAN, John; TONRA, James
Patent: WO2014/55999 A2, 2014 ;
