4-(2-氟苯基)-1,2,3,6-四氢-1-甲基-吡啶合成路线 （共 18 条）
反应条件
boron trifluoride; acetic acid; phenylmethanethiol
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
1: 1.) n-BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, from -60 deg C to RT
2: BF3, glacial AcOH / 15 h / 60 °C
View Scheme
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
1: 1.) n-BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, from -60 deg C to RT
2: BF3, glacial AcOH / 15 h / 60 °C
View Scheme
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
反应条件
boron trifluoride; acetic acid
T=60°C; 15 h;
参考文献
Ong; Profitt; Anderson; Kruse; Wilker; Geyer III
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 74 - 79
