2-氯-4-碘-1-甲氧基苯合成路线 （共 9 条）
反应条件
2,4,6-tris[(4-dichloroiodo)phenoxy]-1,3,5-triazine in dichloromethane
T=20°C; 4 h;
参考文献
Thorat, Prerana B.; Bhong, Bhagyashree Y.; Karade, Nandkishor Y.
Synlett, 2013 , vol. 24, # 16 art. no. ST-2013-D0533-L, p. 2061 - 2066
反应条件
1: With pyridine in dichloromethane
T=0°C; 3 h;
2: With hydrogenchloride in 1,4-dioxane
T=0°C; 1 h;
参考文献
Chen, Jiang-Min; Zeng, Xiao-Mei; Middleton, Kyle; Zhdankin, Viktor V.
Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1952 - 1955
反应条件
1: With hydrogenchloride in water
Heating;
2: With sodium iodide; sodium nitrite in water
T=-5 - 20°C;
参考文献
Malysheva, Yulia B.; Combes, Sebastien; Fedorov, Alexey Yu.; Knochel, Paul; Gavryushin, Andrei E.
Synlett, 2012 , vol. 23, # 8 p. 1205 - 1208
反应条件
phenyltrimethylammonium dichloroiodate; 1-n-butyl-3-methylimidazolium hexafluorophosphate
T=100°C; 3 h;
参考文献
Tilve, Rutuja D.; Kanetkar, Vinod R.
Synthetic Communications, 2005 , vol. 35, # 10 p. 1313 - 1318
反应条件
potassium carbonate in acetone
14 h; Heating;
参考文献
Xu, Guozhang; Hartman, Tracy L.; Wargo, Heather; Turpin, Jim A.; Buckheit Jr., Robert W.; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 2 p. 283 - 290
反应条件
hydrogenchloride; 2,2,2-trifluoroethanol; dihydrogen peroxide in water
T=20°C; 2 h;
参考文献
Podgorsek, Ajda; Iskra, Jernej
Molecules, 2010 , vol. 15, # 4 p. 2857 - 2871
反应条件
trifluoroacetic acid; potassium iodide in water
Yield given;
参考文献
Foster, Natalie I.; Heindel, Ned D.; Burns, Donald H.; Muhr, William
Synthesis, 1980 , # 7 p. 572 - 573
反应条件
1: 99 percent / NaI; NaOH; NaOCl / methanol; H2O / 2 h / 23 °C
2: 94 percent / K2CO3 / acetone / 14 h / Heating
View Scheme
参考文献
Xu, Guozhang; Hartman, Tracy L.; Wargo, Heather; Turpin, Jim A.; Buckheit Jr., Robert W.; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 2 p. 283 - 290
反应条件
Erwaermen auf dem Dampfbad;
参考文献
Matheson; McCombie
Journal of the Chemical Society, 1931 , p. 1103,1108
