6-溴-1a,2,3,7b-四氢-1-噁-环丙[a]萘合成路线 （共 3 条）
反应条件
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid in dichloromethane
2.5 h; Ambient temperature;
参考文献
Saito, Masahiko; Kayama, Yasutaka; Watanabe, Tamaki; Fukushima, Hisashi; Hara, Takeshi; et al.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1364 - 1372
反应条件
1: NaBH4 / ethanol / 2 h / Ambient temperature
2: 1.3 g / p-toluenesulfonc acid / benzene / 0.67 h / Heating
3: N-bromoacetamide / tetrahydrofuran; H2O / 1 h / Ambient temperature
4: t-BuOK / benzene / 2 h / Ambient temperature
View Scheme
参考文献
Chini, Marco; Crotti, Paolo; Minutolo, Filippo; Martinelli, Adriano; Micali, Eugenio
Gazzetta Chimica Italiana, 1994 , vol. 124, # 1 p. 27 - 34
反应条件
1: 1.3 g / p-toluenesulfonc acid / benzene / 0.67 h / Heating
2: N-bromoacetamide / tetrahydrofuran; H2O / 1 h / Ambient temperature
3: t-BuOK / benzene / 2 h / Ambient temperature
View Scheme
参考文献
Chini, Marco; Crotti, Paolo; Minutolo, Filippo; Martinelli, Adriano; Micali, Eugenio
Gazzetta Chimica Italiana, 1994 , vol. 124, # 1 p. 27 - 34
