1: 94 percent / lithium / ethane-1,2-diamine 2: pyridine 3: 53 percent / 2,6-lutidine / acetone; H2O / 20 h / 60 °C / other solvents (dioxane, methanol), other temperatures (40 deg C - 60 deg C); rate constants, ΔH(act.), ΔS(act.) View Scheme