7-甲基-5-硝基-1H-吲唑合成路线 （共 3 条）
反应条件
hydrazine hydrate in acetonitrile
Reflux;
参考文献
Le Fur, Nicolas; Hochart, Guillaume; Larchanche, Paul-Emmanuel; Melnyk, Patricia
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3052 - 3057
反应条件
1.1: trifluorormethanesulfonic acid / 0.33 h / 0 °C
1.2: 0 - 20 °C
2.1: hydrazine hydrate / acetonitrile / Reflux
View Scheme
参考文献
Le Fur, Nicolas; Hochart, Guillaume; Larchanche, Paul-Emmanuel; Melnyk, Patricia
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3052 - 3057
反应条件
hydrogenchloride; nitrous gases; potassium acetate
1) 4-5 h, benzene, 80-85 deg C, 2) 45-60 deg C, 100 min; Yield given. Multistep reaction;
参考文献
Ruechardt, Christoph; Hassmann, Volker
Liebigs Annalen der Chemie, 1980 , # 6 p. 908 - 927
