7-氯-3-二甲基氨基-2,4-二氧代-1H-喹唑啉-6-磺酰胺合成路线 （共 5 条）
反应条件
ammonium hydroxide
1 h;
参考文献
Baronnet; Callendret; Blanchard; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247
反应条件
1: ethanol / 60 °C
2: aq. HCl / 1.5 h
3: ClSO3H / 3 h / 100 °C
4: 63 percent / concd. NH3 solution / 1 h
View Scheme
参考文献
Baronnet; Callendret; Blanchard; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247
反应条件
1: aq. HCl / 1.5 h
2: ClSO3H / 3 h / 100 °C
3: 63 percent / concd. NH3 solution / 1 h
View Scheme
参考文献
Baronnet; Callendret; Blanchard; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247
反应条件
1: dioxane / 1.5 h / 40 °C
2: ethanol / 60 °C
3: aq. HCl / 1.5 h
4: ClSO3H / 3 h / 100 °C
5: 63 percent / concd. NH3 solution / 1 h
View Scheme
参考文献
Baronnet; Callendret; Blanchard; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247
反应条件
1: ClSO3H / 3 h / 100 °C
2: 63 percent / concd. NH3 solution / 1 h
View Scheme
参考文献
Baronnet; Callendret; Blanchard; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247
