3-(1-甲基乙氧基)-苯甲醛合成路线 （共 12 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 42 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2008/194535 A1, 2008 ;
Location in patent: Page/Page column 36-37 ;
US 20080194535 A1
反应条件
n-butyllithium in tetrahydrofuran; hexane; ethyl acetate; N,N-dimethyl-formamide
参考文献
Abbott Laboratories
Patent: US6284796 B1, 2001 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Cortes Morales, Julio Cesar; Guillen Torres, Alejandro; Gonzalez-Zamora, Eduardo
European Journal of Organic Chemistry, 2011 , # 17 p. 3165 - 3170
反应条件
sodium hydroxide in water; N,N-dimethyl-formamide
参考文献
US5674881 A1, ;
US 5674881 A
反应条件
in dimethyl sulfoxide
参考文献
Abbott Laboratories
Patent: US5120752 A1, 1992 ;
参考文献
Medivir AB
Patent: US5593993 A1, 1997 ;
反应条件
1: 62 percent / Br2, NaOAc / CH2Cl2 2: 61 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 6 h, 2.) r.t., overnight 3: 97 percent / 90percent aq. TFA / 3 h 4: 89 percent / 6 h / Heating View Scheme
参考文献
Bringmann, Gerhard; Goetz, Roland; Keller, Paul A.; Walter, Rainer; Henschel, Petra; et al.
Heterocycles, 1994 , vol. 39, # 2 p. 503 - 508
反应条件
sodium borohydride in ethanol; water
参考文献
Sterling Winthrop Inc.
Patent: US5554620 A1, 1996 ;
反应条件
1: 62 percent / Br2, NaOAc / CH2Cl2 2: 61 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 6 h, 2.) r.t., overnight 3: 97 percent / 90percent aq. TFA / 3 h 4: 89 percent / 6 h / Heating 5: 95 percent / ethanol / 4 h / Ambient temperature 6: 97 percent / K2CO3 / acetone / 10 h / Heating View Scheme
参考文献
Bringmann, Gerhard; Goetz, Roland; Keller, Paul A.; Walter, Rainer; Henschel, Petra; et al.
Heterocycles, 1994 , vol. 39, # 2 p. 503 - 508
反应条件
1: 62 percent / Br2, NaOAc / CH2Cl2 2: 61 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 6 h, 2.) r.t., overnight 3: 97 percent / 90percent aq. TFA / 3 h 4: 89 percent / 6 h / Heating 5: 95 percent / ethanol / 4 h / Ambient temperature View Scheme
参考文献
Bringmann, Gerhard; Goetz, Roland; Keller, Paul A.; Walter, Rainer; Henschel, Petra; et al.
Heterocycles, 1994 , vol. 39, # 2 p. 503 - 508
