5-溴-3-碘-7-氮杂吲哚合成路线 （共 3 条）
反应条件
N-iodo-succinimide in acetone T=20°C; 0.333333 h;
参考文献
UNIVERSITY OF ROCHESTER; BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA; GELBARD, Harris A.; DEWHURST, Stephen; GENDELMAN, Howard E.
Patent: WO2014/85795 A1, 2014 ;
Location in patent: Paragraph 0400 ;
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water
2.75 h;
参考文献
Gourdain, Stephanie; Dairou, Julien; Denhez, Clement; Bui, Linh Chi; Rodrigues-Lima, Fernando; Janel, Nathalie; Delabar, Jean M.; Cariou, Kevin; Dodd, Robert H.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9569 - 9585
反应条件
sodium hydride in tetrahydrofuran
T=20°C; 4 h;
参考文献
SGX Pharmaceuticals, Inc.
Patent: US2006/30583 A1, 2006 ;
Location in patent: Page/Page column 78 ;
US 20060030583 A1
