2-溴-3-氯-5-(三氟甲基)吡啶合成路线 (共 4 条)
反应条件
trimethylsilyl bromide T=100°C; 15 h; Inert atmosphere;
参考文献
Tsoung, Jennifer; Panteleev, Jane; Tesch, Matthias; Lautens, Mark
Organic Letters, 2014 , vol. 16, # 1 p. 110 - 113
反应条件
n-butyllithium in diethyl ether; hexane; nitrogen; water
反应条件
in N-methyl-acetamide; diethyl ether
反应条件
water; sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in dimethyl sulfoxide
16 h;
参考文献
BAYER CROPSCIENCE AG
Patent: WO2005/4606 A2, 2005 ;
Location in patent: Page/Page column 64 ;