反应条件
1: PBr3, pyridine / diethyl ether
2: 1a.) ethylmagnesium bromide, 1b.) cuprous chloride / 1a.) THF, reflux, 6 h, 1b.) 0 deg C, 15 min, 3.) reflux, 9 h
3: 66 percent / p-TsOH / methanol / 4 h / Heating
4: 92 percent / H2, quinoline / Lindlar's catalyst / hexane / Ambient temperature
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Kumari, Sarla; Rani, Veena
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 769 - 770
