5-甲基喹唑啉-4(1H)-酮合成路线 （共 6 条）
参考文献
Kulkarni, Shridhar S.; Singh, Satyakam; Shah, Janki R.; Low, Woon-Kai; Talele, Tanaji T.
European Journal of Medicinal Chemistry, 2012 , vol. 50, p. 264 - 273
反应条件
1: 2-methyl-6-nitrobenzonitrile With iron(III) chloride; hydrazine hydrate in methanol; water 3 h; Heating; 2: formic acid With hydrogenchloride in water T=90 - 130°C; Further stages.;
参考文献
Chandregowda, Venkateshappa; Venkateswara Rao, Gudapati; Chandrasekara Reddy, Goukanapalli
Heterocycles, 2007 , vol. 71, # 1 p. 39 - 48
反应条件
1: 55 percent / FeSO4*7H2O, 32 percent aq. ammonia / H2O / 0.08 h / Heating 2: 0.25 h / 235 °C View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 327, # 5 p. 865 - 867
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: ferrosulfate; ammonia 4: 210 °C View Scheme
参考文献
Chemische Berichte, , vol. 52, p. 1083
反应条件
1: potassium nitrite; sulfuric acid 2: ferrosulfate; ammonia 3: 210 °C View Scheme
参考文献
Chemische Berichte, , vol. 52, p. 1083
反应条件
bis-(2-hydroxy-ethyl)-amine; trichlorophosphate in toluene
0.5 h; Heating / reflux;
参考文献
Gavai, Ashvinikumar V.; Chen, Ping; Zhao, Yufen
Patent: US2006/217369 A1, 2006 ;
Location in patent: Page/Page column 10 ;
US 20060217369 A1
