1-[6-[2-(二丙基氨基)乙氧基]-4,7-二甲氧基-1-苯并呋喃-5-基]-3-甲基脲合成路线 （共 5 条）
反应条件
potassium carbonate in acetonitrile
4 h; Heating;
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 90 percent / HCl / ethanol / 20 h / Heating
2: 89 percent / CHCl3 / 2 h / Ambient temperature
3: 77 percent / K2CO3 / acetonitrile / 4 h / Heating
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 82 percent / hydroxylamine hydrochloride, conc. NaOH / ethanol; H2O / 6 h / Heating
2: 75 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C
3: 90 percent / HCl / ethanol / 20 h / Heating
4: 89 percent / CHCl3 / 2 h / Ambient temperature
5: 77 percent / K2CO3 / acetonitrile / 4 h / Heating
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 75 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C
2: 90 percent / HCl / ethanol / 20 h / Heating
3: 89 percent / CHCl3 / 2 h / Ambient temperature
4: 77 percent / K2CO3 / acetonitrile / 4 h / Heating
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 89 percent / CHCl3 / 2 h / Ambient temperature
2: 77 percent / K2CO3 / acetonitrile / 4 h / Heating
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
