(3,5,6-三甲基吡嗪-2-基)甲醇合成路线 （共 10 条）
反应条件
water; sodium hydroxide
参考文献
Bohman, Bjoern; Jeffares, Lynne; Barrow, Russell A.; Phillips, Ryan D.; Peakall, Rod; Flematti, Gavin; Dixon, Kingsley W.; Byrne, Lindsay T.; Skelton, Brian W.
Journal of Natural Products, 2012 , vol. 75, # 9 p. 1589 - 1594,6
反应条件
1: hydrogen peroxide; glacial acetic acid / Heating 2: 2 h / Heating 3: aq. NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 10 p. 3315 - 3320
反应条件
1: 2 h / Heating 2: aq. NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 10 p. 3315 - 3320
反应条件
1: 93 percent / dimethylformamide / 12 h / Ambient temperature 2: 1.) Ag2O, 2.) phenothiazine / 1.) H2O, 30 min., 2.) toluene, reflux 3: toluene / Heating View Scheme
参考文献
Chemische Berichte, , vol. 123, p. 523 - 533
反应条件
1: 1.) Ag2O, 2.) phenothiazine / 1.) H2O, 30 min., 2.) toluene, reflux 2: toluene / Heating View Scheme
参考文献
Chemische Berichte, , vol. 123, p. 523 - 533
反应条件
oxygen; lithium diisopropyl amide 1)ether, hexane, room temp., 1h 2)0 deg C, 60 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 17, p. 647 - 649
反应条件
in toluene Heating; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Chemische Berichte, , vol. 123, p. 523 - 533
反应条件
potassium permanganate in water T=20°C; 0.666667 h;
参考文献
Li, Zhenyu; Yu, Fang; Zhan, Peng; Shen, Yuemao; Liu, Xinyong; Cui, Lei; Wang, Shouxun
Medicinal Chemistry, 2012 , vol. 8, # 5 p. 928 - 933,6
反应条件
phosphoric acid; dicyclohexyl-carbodiimide in dimethyl sulfoxide Pfitzner-Moffatt oxidation;
参考文献
Deng, Lijuan; Guo, Xiuli; Zhai, Li; Song, Yuning; Chen, Hongfei; Zhan, Peng; Wu, Jingde; Liu, Xinyong
Chemical Biology and Drug Design, 2012 , vol. 79, # 5 p. 731 - 739
反应条件
1: 100 percent / thionyl chloride / CH2Cl2 / 2.5 h
2: 50 percent / CHCl3 / 5 h / 20 °C
View Scheme
参考文献
Cheng, Xian-Chao; Liu, Xin-Yong; Xu, Wen-Fang; Guo, Xiu-Li; Ou, Yang
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 10 p. 3315 - 3320
