6-(苄氧基)吡啶-3-胺合成路线 （共 4 条）
反应条件
in benzyl alcohol
T=120°C; 16 h;
参考文献
Kelly, Martha; Lee, Younghee; Liu, Bin; Fujimoto, Ted; Freundlich, Joel; Dorsey, Bruce D.; Flynn, Gary A.; Husain, Arifa
Patent: US2006/270686 A1, 2006 ;
Location in patent: Page/Page column 34 ;
参考文献
LOCUS PHARMACEUTICALS, INC.
Patent: WO2008/8059 A1, 2008 ;
Location in patent: Page/Page column 92 ;
反应条件
1: benzyl alcohol
2: iron-powder; acetic acid; aqueous methanol
View Scheme
参考文献
Friedman et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 1204
反应条件
1: 18-crown-6 ether; potassium hydroxide / toluene / 0.5 h / Inert atmosphere; Reflux
2: palladium 10 on activated carbon; hydrogen / ethyl acetate / 6 h / 20 °C / 3750.38 Torr / Autoclave
View Scheme
参考文献
Baragona, Fabien; Lomberget, Thierry; Duchamp, Christian; Henriques, Natali; Lo Piccolo, Eugenio; Diana, Patrizia; Montalbano, Alessandra; Barret, Roland
Tetrahedron, 2011 , vol. 67, # 45 p. 8731 - 8739
