triethylamine in tetrahydrofuran; water; acetonitrile T=20°C; pH=8.5; 3 h;

暂无反应条件数据

TEA in water; N,N-dimethyl-formamide 1 h;

ethylenediaminetetraacetic acid; tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide T=25°C; 1 h; Yield given;

1: ε-FmocHN-Lys(α-Fmoc)OH With N-ethyl-N,N-diisopropylamine solid phase reaction; 2: With piperidine in N,N-dimethyl-formamide solid phase reaction; 3: 5-dimethylamino-1-naphthalenesulfonyl chloride Further stages;

1: Fmoc-DL-Ala-OH With N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate; [3H]-Strychnine in acetonitrile T=0°C; 0.25 h; 2: With 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine in dichloromethane; acetonitrile 10 h; Wang resin; 3: Fmoc-DL-Ala-OH; acetic anhydride; ε-FmocHN-Lys(α-Fmoc)OH Further stages;