1: 42 percent / KOH; water / 0.5 h / 75 °C 2: 54 percent / conc. HCl; SnCl2*H2O / methanol / Heating View Scheme
参考文献
Stankyavichyus, A. P.; Terent'ev, P. B.; Bolotin, V. A.; Lashin, V. V.; Rakhimi, I. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , p. 403 - 409
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , vol. 24, # 4 p. 491 - 498
1: With potassium hydroxide; water T=75°C; 0.5 h; 2: With hydrogen; palladium on activated charcoal in methanol; dichloromethane T=50°C; P=2250.23 Torr; Further stages.;
1: 6-nitro-1H-indazole With sodium hydride in N,N-dimethyl-formamide T=20°C; 0.333333 h; 2: methyl iodide in N,N-dimethyl-formamide
参考文献
The United States of America, as represented by the Secretary, Department of Health and Human Services; Science Applications International Corporation (SAIC); Albany Molecular Research, Inc.
Patent: WO2009/42907 A1, 2009 ;
Location in patent: Page/Page column 84 ;
WO 2009/042907 A1
