2-氯-4,6-二吗啉-4-基-1,3,5-三嗪合成路线 （共 5 条）
反应条件
in isopropyl alcohol T=50 - 80°C; ΔH(exces.), ΔS(exces.); Rate constantThermodynamic data;
参考文献
Just, Gerhard; Pokorny, Ina; Pritzkow, Wilhelm
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1995 , vol. 337, # 2 p. 133 - 135
反应条件
hydrazine in ethanol 3 h; Heating / reflux;
参考文献
Kudos Pharmaceuticals Ltd
Patent: US2006/199804 A1, 2006 ;
Location in patent: Page/Page column 17 ;
US 20060199804 A1
反应条件
sodium hydrogencarbonate in dichloromethane
T=0 - 40°C; 3 h;
参考文献
Misawa, Takashi; Salim, Mohammed T.A.; Okamoto, Mika; Baba, Masanori; Aoyama, Hiroshi; Hashimoto, Yuichi; Sugita, Kazuyuki
Heterocycles, 2010 , vol. 81, # 6 p. 1419 - 1428
反应条件
sodium carbonate in water; acetone
T=35 - 45°C;
参考文献
Kumar, Nitin; Khan, Shabana I.; Rawat, Diwan S.
Helvetica Chimica Acta, 2012 , vol. 95, # 7 p. 1181 - 1197
反应条件
in tetrahydrofuran
T=0°C; Inert atmosphere;
参考文献
Nakamura, Hiroyuki; Shoji, Atsushi; Takeuchi, Ayano; Ban, Hyun Seung; Lee, Jong-Dae; Yamori, Takao; Kang, Sang Ook
Australian Journal of Chemistry, 2011 , vol. 64, # 11 p. 1430 - 1437
