3-(2-萘基氧基)-1-丙醇合成路线 （共 22 条）
反应条件
C19H20N4 in N,N-dimethyl-formamide; mineral oil
T=110°C; 18 h; Inert atmosphere;
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
反应条件
tetrabutyl ammonium fluoride; water
T=70°C; 1 h;
参考文献
Kim, Dong Wook; Jeong, Hwan-Jeong; Lim, Seok Tae; Sohn, Myung-Hee
Angewandte Chemie - International Edition, 2008 , vol. 47, # 44 p. 8404 - 8406
反应条件
sodium hydrogencarbonate
T=150°C; 24 h; Ionic liquid;
参考文献
Hong, Dong Jin; Kim, Dong Wook; Chi, Dae Yoon
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 54 - 56
参考文献
Searles; Butler
Journal of the American Chemical Society, 1954 , vol. 76, p. 56
参考文献
Rindfusz; Ginnings; Harnack
Journal of the American Chemical Society, 1920 , vol. 42, p. 163
反应条件
1: N-iodo-succinimide / dichloromethane / -78 - 20 °C / Inert atmosphere
2: N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere
View Scheme
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: N-iodo-succinimide / dichloromethane / -78 - 20 °C / Inert atmosphere
3.1: N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere
View Scheme
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
反应条件
1.1: sodium carbonate / acetonitrile / 72 h / 80 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 20 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: N-iodo-succinimide / dichloromethane / -78 - 20 °C / Inert atmosphere
4.1: N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere
View Scheme
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
反应条件
1: N-iodo-succinimide / dichloromethane / -78 - 20 °C / Inert atmosphere
2: C19H20N4 / N,N-dimethyl-formamide; mineral oil / 18 h / 110 °C / Inert atmosphere
View Scheme
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: N-iodo-succinimide / dichloromethane / -78 - 20 °C / Inert atmosphere
3.1: C19H20N4 / N,N-dimethyl-formamide; mineral oil / 18 h / 110 °C / Inert atmosphere
View Scheme
参考文献
Sword, Ryan; Baldwin, Luke A.; Murphy, John A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3560 - 3570
