1: 1.) trifluoroacetic acid, 2.) water / 1.) 80 deg C, 4 h, 2.) RT, 20 min 2: 82 percent / NaH, dicyclohexyl-18-crown-6 / toluene / 48 h / Ambient temperature 3: 95 percent / 0.1N aq. NaOH / methanol / 1.5 h View Scheme