3-氯-6-甲氧基苯并[b]噻吩-2-甲酰氯合成路线 (共 6 条)
反应条件
pyridine; thionyl chloride in N,N-dimethyl-formamide T=140°C; 0.5 h;
参考文献
Pakray; Castle
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 5 p. 1571 - 1577
反应条件
pyridine; thionyl chloride T=105°C; 48 h;
参考文献
Moloney, Gerard P.; Angus, James A.; Robertson, Alan D.; Stoermer, Martin J.; Robinson, Michael; Lay, Lucy; Wright, Christine E.; McRae, Ken; Christopoulos, Arthur
Australian Journal of Chemistry, 2008 , vol. 61, # 7 p. 484 - 499
反应条件
thionyl chloride in pyridine; tert-butyl methyl ether
反应条件
pyridine; thionyl chloride T=140°C; 0.5 h;
参考文献
Ried, Walter; Oremek, Gerhard; Ocakcioglu, Belkis
Liebigs Annalen der Chemie, 1980 , # 9 p. 1424 - 1427
反应条件
chlorine in chloroform 1.25 h; Ambient temperature;
参考文献
Connor; Cetenko; Mullican; Sorenson; Unangst; Weikert; Adolphson; Kennedy; Thueson; Wright; Conroy
Journal of Medicinal Chemistry, 1992 , vol. 35, # 5 p. 958 - 965
反应条件
chloro-trimethyl-silane in methanol; ethanol; hexane
参考文献
Geron Corporation
Patent: US5863936 A1, 1999 ;