2,2,3,3-四氟丙醇合成路线 （共 89 条）
反应条件
(i), (ii) H2O; Multistep reaction;
参考文献
Dedek,V. et al.
Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, p. 985 - 997
反应条件
phosphonitrilic chloride trimer; sodium in tetrahydrofuran
参考文献
Gol'din,G.S. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 688 - 691,685 - 688
反应条件
pyridine in nitrobenzene
T=90 - 95°C; 1 h;
参考文献
Gol'din, G. S.; Fedorov, S. G.; Kotova, E. V.; Bochkarev, V. N.; Slyusarenko, T. F.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 1 p. 21 - 23,15 - 17
反应条件
phosphonitrilic chloride trimer; sodium in tetrahydrofuran
参考文献
Gol'din,G.S. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 688 - 691,685 - 688
反应条件
pyridine in nitrobenzene
T=90 - 95°C; 5 h; various initial molar ratios of reagents; various reaction times.; Product distribution;
参考文献
Gol'din, G. S.; Fedorov, S. G.; Kotova, E. V.; Bochkarev, V. N.; Slyusarenko, T. F.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 1 p. 21 - 23,15 - 17
反应条件
T=0 - 75°C; 4 h; TemperatureTimeConcentration;
参考文献
BAYER INTELLECTUAL PROPERTY GMBH; FEY, Peter
Patent: US2013/143900 A1, 2013 ;
Location in patent: Paragraph 0160; 0161; 0162 ;
参考文献
Flynn, Richard M.; Bulinski, Michael J.; Costello, Michael G.
Patent: US2010/108934 A1, 2010 ;
Location in patent: Page/Page column 4-5 ;
参考文献
Gmelin Handbook: F: PerFHalOrg.2, 1.3.4, page 137 - 166
反应条件
ammonia; tetra-n-propylammonium bromide in water
T=0 - 6°C; 5 h; Product distribution / selectivity;
参考文献
Central Glass Co., Ltd
Patent: JP2005/314356 A, 2005 ;
Location in patent: Page/Page column 10-11; 13 ;
反应条件
triethylamine
T=4.3 - 10.2°C; 2.5 h; Neat (no solvent); Product distribution / selectivity;
参考文献
Central Glass Co., Ltd
Patent: JP2005/314356 A, 2005 ;
Location in patent: Page/Page column 14-15 ;
