反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C / |Inert atmosphere 1.2: 1.5 h / 0 - 20 °C / |Inert atmosphere 2.1: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / N,N-dimethyl-formamide / 16 h / 105 °C / |Inert atmosphere View Scheme
参考文献
Jimenez, Juan-Miguel; Boyall, Dean; Brenchley, Guy; Collier, Philip N.; Davis, Christopher J.; Fraysse, Damien; Keily, Shazia B.; Henderson, Jaclyn; Miller, Andrew; Pierard, Francoise; Settimo, Luca; Twin, Heather C.; Bolton, Claire M.; Curnock, Adam P.; Chiu, Peter; Tanner, Adam J.; Young, Stephen
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 1799 - 1810