1: triethylamine / dichloromethane; N,N-dimethyl-formamide / 3 h / 4 - 20 °C
2: piperidine / methanol / 2 h / 20 °C
View Scheme
参考文献
Wang, Fang; Good, James A. D.; Rath, Oliver; Kaan, Hung Yi Kristal; Sutcliffe, Oliver B.; MacKay, Simon P.; Kozielski, Frank
Journal of Medicinal Chemistry, 2012 , vol. 55, # 4 p. 1511 - 1525