7-甲氧基-1H-吡唑并[3,4-c]吡啶合成路线 （共 6 条）
反应条件
1: hydrochloric acid 2: 67 percent / phosphorus pentasulphide / pyridine / 4.5 h / Heating 3: 71 percent / chlorine, conc. hydrochloric acid / 0.33 h View Scheme
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
反应条件
1: 54 percent / toluene / 2 h / 100 °C
2: 1.) phosphorus pentaoxide, potassium acetate, nitrosyl chloride, 2.) sodium carbonate / 1.) acetic acid, 30 min, 2.) benzene, 2 h, reflux
View Scheme
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
反应条件
P2O5; potassium acetate; sodium carbonate; nitrosyl chloride
1.) acetic acid, 30 min, 2.) benzene, 2 h, reflux; Yield given. Multistep reaction;
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
反应条件
sodium hydride in N,N-dimethyl-formamide
Heating;
参考文献
Kourafalos, Vassilios N.; Marakos, Panagiotis; Mikros, Emmanuel; Pouli, Nicole; Marek, Jaromir; Marek, Radek
Tetrahedron, 2006 , vol. 62, # 51 p. 11987 - 11993
反应条件
sodium hydride in N,N-dimethyl-formamide
Heating;
参考文献
Kourafalos, Vassilios N.; Marakos, Panagiotis; Mikros, Emmanuel; Pouli, Nicole; Marek, Jaromir; Marek, Radek
Tetrahedron, 2006 , vol. 62, # 51 p. 11987 - 11993
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
