N,N-二乙基-2-溴苯甲酰胺合成路线 （共 19 条）
反应条件
in dichloromethane T=0 - 20°C; Schlenk technique;
参考文献
Wertjes, William C.; Wolfe, Lydia C.; Waller, Peter J.; Kalyani, Dipannita
Organic Letters, 2013 , vol. 15, # 23 p. 5986 - 5989
反应条件
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine in acetonitrile T=0 - 25°C;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 19 p. 5893 - 5896
反应条件
iodine; N-ethyl-N,N-diisopropylamine; triphenylphosphine in dichloromethane T=0 - 20°C; 2 h;
参考文献
Kumar, Amit; Akula, Hari Kiran; Lakshman, Mahesh K.
European Journal of Organic Chemistry, 2010 , # 14 p. 2709 - 2715
反应条件
bromine in dichloromethane Heating;
参考文献
Zhao, Zhongdong; Snieckus, Victor
Organic Letters, 2005 , vol. 7, # 13 p. 2523 - 2526
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium; bromine; mercury dichloride in tetrahydrofuran T=0°C; 0.333333 h; other LiTMP/HgCl2 molar ratio, var. orthoactivated aromatic compounds; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 53, # 12 p. 2728 - 2732
反应条件
N,N,N',N,-tetramethylethylenediamine; 1,2-dibromo-1,1,2,2-tetrafluoroethane; sec.-butyllithium 1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 48, # 23 p. 4863 - 4878
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium; allyl bromide Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 36, # 7 p. 1039 - 1042
反应条件
N,N,N',N,-tetramethylethylenediamine; N,N-diethyl benzamide; sec.-butyllithium Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 36, # 7 p. 1039 - 1042
反应条件
sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=90 - 100°C;
参考文献
MacNeil, Stephen L.; Gray, Matthew; Gusev, Dmitry G.; Briggs, Laura E.; Snieckus, Victor
Journal of Organic Chemistry, 2008 , vol. 73, # 24 p. 9710 - 9719
反应条件
1: 81 percent / t-BuONa / Pd2(dba)3, BINAP / toluene / 21 h / 90 - 100 °C 2: 98 percent 3: 79 percent / LDA / tetrahydrofuran / 1.5 h / 0 °C View Scheme
参考文献
MacNeil, Stephen L.; Gray, Matthew; Briggs, Laura E.; Li, Jim J.; Snieckus
Synlett, 1998 , # 4 p. 419 - 421
