lithium aluminium tetrahydride in diethyl ether 20 h; Heating;

1: 68 percent / lithium aluminium hydride / diethyl ether / 20 h / Heating 2: 93 percent / potassium carbonate / methanol; H2O / 3 h 3: 90 percent / lithium diisopropylamide, HMPA / tetrahydrofuran / -78 deg C -> room temperature, overnight 4: 1.) DIBAL-H, 2.) 6percent aq. sulfuric acid / 1.) toluene, hexane, 0 deg C, 3 h, 2.) room temperature, 1 h 5: lithium diisopropylamide, anhydrous zinc chloride / tetrahydrofuran; diethyl ether / -10 °C View Scheme