2-甲基-8-(苯基甲氧基)咪唑并[1,2-a]吡啶-3-乙腈合成路线 （共 7 条）
反应条件
triethylamine in ethanol
24 h; Heating;
参考文献
Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892
反应条件
trifluoroacetic anhydride in 1,4-dioxane
参考文献
Schering Corporation
Patent: US4450164 A1, 1984 ;
反应条件
in N,N-dimethyl-formamide
参考文献
Schering Corporation
Patent: US4450164 A1, 1984 ;
反应条件
in N,N-dimethyl-formamide
1 h; Heating;
参考文献
Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892
反应条件
1: 45 percent / etheral hydrogen chloride, sulfuryl chloride / ethanol / 2.75 h / 20 °C
2: triethylamine / ethanol / 24 h / Heating
View Scheme
参考文献
Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892
反应条件
cyclohexa-1,4-diene; palladium in N,N-dimethyl-formamide
T=75 - 80°C; 1 h;
参考文献
Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892
反应条件
palladium in N-methyl-acetamide
参考文献
Schering Corporation
Patent: US4450164 A1, 1984 ;
