3-(2-氯苯基)-3-氧代丙酸合成路线 （共 3 条）
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 5 h;
参考文献
Hogenkamp, Derk J.; Johnstone, Timothy B. C.; Huang, Jin-Cheng; Li, Wen-Yen; Tran, Minhtam; Whittemore, Edward R.; Bagnera, Rudy E.; Gee, Kelvin W.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3369 - 3379
反应条件
1: 5 h / Heating
2: 80 percent / trifluoroacetic acid / CH2Cl2 / 5 h / 20 °C
View Scheme
参考文献
Hogenkamp, Derk J.; Johnstone, Timothy B. C.; Huang, Jin-Cheng; Li, Wen-Yen; Tran, Minhtam; Whittemore, Edward R.; Bagnera, Rudy E.; Gee, Kelvin W.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3369 - 3379
反应条件
1: 4-(dimethylamino)pyridine / CH2Cl2 / -10 - 20 °C
2: 5 h / Heating
3: 80 percent / trifluoroacetic acid / CH2Cl2 / 5 h / 20 °C
View Scheme
参考文献
Hogenkamp, Derk J.; Johnstone, Timothy B. C.; Huang, Jin-Cheng; Li, Wen-Yen; Tran, Minhtam; Whittemore, Edward R.; Bagnera, Rudy E.; Gee, Kelvin W.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3369 - 3379
