1: 46 percent / 30percent H2O2 / 10percent Pd/C / CH2Cl2; ethanol / a) 60 deg C, 20 h, b) 60 deg C, 3 h 2: CH2Cl2 / 1 h / 0 °C 3: 67 percent / CH2Cl2; H2O / 0.25 h View Scheme

in dichloromethane; water 0.25 h;

1: aq. hydrogen peroxide / methanol / 1.) room temperature, 48 h, 2.) heating, 2 h; other reagent: m-chloroperbenzoic acid 2: 1.) trifluoroacetic anhydride / 1.) methylene chloride, room temperature, 1 h; heating, 20 min, 2.) water, room temperature, 1 h View Scheme

1: CH2Cl2 / 1 h / 0 °C 2: 67 percent / CH2Cl2; H2O / 0.25 h View Scheme

trifluoroacetic anhydride 1.) methylene chloride, room temperature, 1 h; heating, 20 min, 2.) water, room temperature, 1 h; Yield given. Multistep reaction;

in diethyl ether; benzonitrile T=37°C; phosphate buffer (pH=7.4); var. time; also mitochondrial studies; Product distributionMechanism;