1: With copper(l) iodide; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; DMF (N,N-dimethyl-formamide) T=40°C; Sonogashira Coupling; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran; DMF (N,N-dimethyl-formamide) T=20 - 60°C;

hydrogenchloride in ethanol T=20°C;