1-[4-氨基-3-(甲基氧基)苯基]-4-羟基哌啶合成路线 （共 3 条）
反应条件
hydrogen; acetic acid; palladium 10 on activated carbon in ethanol
T=20°C; P=1551.49 Torr; 16 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/20990 A1, 2009 ;
Location in patent: Page/Page column 96 ;
WO 2009/020990 A1
反应条件
1: potassium carbonate / dimethyl sulfoxide / 20 °C
2: hydrogen; palladium on activated charcoal / methanol / 20 °C
View Scheme
参考文献
Han, Chun; Huang, Zhangjian; Zheng, Chao; Wan, Ledong; Lai, Yisheng; Peng, Sixun; Ding, Ke; Ji, Hongbin; Zhang, Yihua
European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 82 - 90
反应条件
1: potassium carbonate / dimethyl sulfoxide / 20 °C
2: hydrogen; palladium on activated charcoal / methanol / 20 °C
View Scheme
参考文献
Han, Chun; Huang, Zhangjian; Zheng, Chao; Wan, Ledong; Lai, Yisheng; Peng, Sixun; Ding, Ke; Ji, Hongbin; Zhang, Yihua
European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 82 - 90
