1-苄基-1H-吡唑-4-硼酸频哪醇酯合成路线 （共 4 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) chloroform complex in N,N-dimethyl-formamide T=85°C;
参考文献
Kalypsys, Inc
Patent: US8080566 B1, 2011 ;
Location in patent: Page/Page column 57 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; GENENTECH, INC.; BURDICK, Daniel Jon; CHEN, Huifen; WANG, Shumei; WANG, Weiru
Patent: WO2014/60395 A1, 2014 ;
Location in patent: Page/Page column 35 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine in 1,4-dioxane T=80°C; Masuda borylation; 4 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 9 p. 3139 - 3141
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 2 h / 0 - 20 °C 2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) chloroform complex / N,N-dimethyl-formamide / 85 °C View Scheme
