(2-溴苯基)-吡啶-2-基甲酮合成路线 (共 5 条)
反应条件
N-bromosuccinmide; palladium diacetate
12 h; Heating;
参考文献
Arnold, Polly L.; Sanford, Melanie S.; Pearson, Stephen M.
Journal of the American Chemical Society, 2009 , vol. 131, # 39 p. 13912 - 13913
反应条件
manganese(IV) oxide in dichloromethane
24 h;
参考文献
Harrowven, David C.; Sutton, Benjamin J.; Coulton, Steven
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 22 p. 4047 - 4057
反应条件
in tetrahydrofuran
T=20°C; 0.5 h; Inert atmosphere;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron, 2010 , vol. 66, # 17 p. 3135 - 3146
反应条件
1: ortho-dibromobenzene With magnesium in tetrahydrofuran
Inert atmosphere;
2: 2-pyridine carbonitrile in tetrahydrofuran
T=0°C; Inert atmosphere;
3: With hydrogenchloride; water in diethyl ether
0.5 h; Inert atmosphere;
参考文献
Tao, Xiaoming; Li, Wanfang; Ma, Xin; Li, Xiaoming; Fan, Weizheng; Xie, Xiaomin; Ayad, Tahar; Ratovelomanana-Vidal, Virginie; Zhang, Zhaoguo
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 612 - 616
反应条件
manganese(IV) oxide
2.) ether; Yield given. Multistep reaction;
参考文献
Schubert, Ralf; Gruetzmacher, Hans-Friedrich
Organic Mass Spectrometry, 1980 , vol. 15, # 3 p. 122 - 130