[(1R,5S)-6,6-二甲基双环[3.1.1]庚-2-烯-2-基]甲基特戊酸酯合成路线 （共 3 条）
反应条件
1: sodium chromate / acetic acid; acetic anhydride / 72 h / 35 °C 2: lithium tri-tert-butoxyaluminohydride / tetrahydrofuran 3: boron trifluoride etherate / CH2Cl2 / -20 °C 4: lithium aluminum hydride View Scheme
参考文献
Mechoulam, Raphael; Lander, Naftali; Breuer, Aviva; Zahalka, Jamal
Tetrahedron: Asymmetry, 1990 , vol. 1, # 5 p. 315 - 318
反应条件
pyridine
T=20°C; Cooling with ice;
参考文献
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.; BAB, Itai; MECHOULAM, Raphael; BREUER, Aviva; MUSSAI, Naama
Patent: WO2010/41253 A1, 2010 ;
Location in patent: Page/Page column 20 ;
WO 2010/041253 A1
反应条件
1: sodium chromate / acetic acid; acetic anhydride / 72 h / 35 °C
2: lithium tri-tert-butoxyaluminohydride / tetrahydrofuran
3: boron trifluoride etherate / CH2Cl2 / -20 °C
View Scheme
参考文献
Mechoulam, Raphael; Lander, Naftali; Breuer, Aviva; Zahalka, Jamal
Tetrahedron: Asymmetry, 1990 , vol. 1, # 5 p. 315 - 318
