2-(吡啶-3-基氧基)-苯胺合成路线 (共 4 条)
反应条件
hydrogen; palladium on activated charcoal in methyl acetate
3 h; Ambient temperature;
参考文献
Garanti, Luisa; Molteni, Giorgio; Zecchi, Gaetano
Journal of Chemical Research, Synopses, 1995 , # 7 p. 276 - 277
反应条件
1: K2CO3 / dimethylformamide / 80 - 150 °C
2: H2 / Pd/C
View Scheme
参考文献
Huang, Dehua; Poon, Steve F.; Chapman, Deborah F.; Chung, Janice; Cramer, Merryl; Reger, Thomas S.; Roppe, Jeffrey R.; Tehrani, Lida; Cosford, Nicholas D.P.; Smith, Nicholas D.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5473 - 5476
反应条件
1: 1.) NaH, 2.) copper bronze / 1.) DMSO, 2.) DMSO, 165 deg C, 1 h
2: 33 percent / Fe, aq. HOAc / 1 h / 100 °C
View Scheme
参考文献
Butler, Donald E.; Poschel, B. P. H.; Marriott, John G.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 346 - 350
反应条件
1: 1.) potassium hydroxide / 1.) water, 2.) 140 deg C, 3h, 180 deg C, 2h
2: H2, Raney Ni
View Scheme
参考文献
Abramovitch, Rudolph A.; Inbasekaran, Muthiah N.; Kato, Shozo; Radzikowska, Teresa A.; Tomasik, Piotr
Journal of Organic Chemistry, 1983 , vol. 48, # 5 p. 690 - 695