R-(+)-1,1'-联萘-2,2'-双二苯膦合成路线 （共 19 条）
反应条件
tributylphosphine; iodine in tetrahydrofuran; acetonitrile T=20°C; 0.166667 h; Inert atmosphere;
参考文献
WO2011/123037 A1, ;
Page/Page column 1 ;
反应条件
1: bis-diphenylphosphine With Cl2Ni(1,2-bis(diphenylphosphino)ethane) in DMF (N,N-dimethyl-formamide) T=20 - 100°C; 0.5 h; 2: binaphthol bis(nonafluoro-n-butanesulfonate) With 1,4-diaza-bicyclo[2.2.2]octane in DMF (N,N-dimethyl-formamide) T=100°C; 48 h;
参考文献
US6353125 B1, ;
Page column 17 ;
反应条件
trichlorosilane; triethyl phosphite in tetrahydrofuran; toluene T=100°C; 3 h;
参考文献
Organic Letters, , vol. 6, # 25 p. 4675 - 4678
反应条件
sodium hydroxide; trichlorosilane; 2,3-dimethyl aniline in toluene
反应条件
tert.-butyl lithium in tetrahydrofuran
参考文献
Journal of the American Chemical Society, , vol. 102, # 27 p. 7932 - 7934
反应条件
1,4-diaza-bicyclo[2.2.2]octane; nickel dichloride; zinc T=100°C;
参考文献
US6353125 B1, ;
Page column 17-18 ;
反应条件
1: (R)-2,2'-bis(trifluoromethanesulfonyloxy)-1,1'-binaphthalene With Cl2Ni(1,2-bis(diphenylphosphino)ethane) in N,N-dimethyl-formamide 2: diphenylphosphinous bromide With 1,4-diaza-bicyclo[2.2.2]octane in N,N-dimethyl-formamide T=110°C;
参考文献
Chemistry - A European Journal, , vol. 17, # 39 p. 10828 - 10831
反应条件
1: DBBN With iodine; magnesium in tetrahydrofuran; toluene T=60 - 75°C; 4 h; Inert atmosphere; 2: diphenylphosphinous bromide in tetrahydrofuran; toluene T=60°C; 3 h;
参考文献
Chemistry - A European Journal, , vol. 17, # 39 p. 10828 - 10831
反应条件
1: 45 percent / (C6H5)3PBr2 / 320 °C 2: 78 percent / t-C4H9Li / tetrahydrofuran View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 27 p. 7932 - 7934
反应条件
1,4-diaza-bicyclo[2.2.2]octane; nickel(0){1,2-bis(diphenylphosphino)ethane} in N,N-dimethyl-formamide T=100°C; 72 h;
参考文献
Tetrahedron Letters, , vol. 39, # 13 p. 1773 - 1776
