triethylamine; trichlorophosphate in dichloromethane 1 h; Ambient temperature;

1: 60 percent / NaH (65percent in oil) / tetrahydrofuran / 1) 30 to 35 deg C, 2) RT, 2 h 2: 62 percent / phosphoryl chloride, triethylamine / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 60 percent / NaH (65percent in oil) / tetrahydrofuran / 3 h / 40 - 50 °C 2: NaOH / methanol; H2O / 18 h / 50 °C 3: 48 percent / etanolamine / 1 h / 170 °C View Scheme