1-(4-氯苯基)-2H-吡唑啉-3-酮合成路线 （共 8 条）
反应条件
1: With oxygen; copper(l) chloride in N,N-dimethyl-formamide T=20°C; 3 h; 2: With water in N,N-dimethyl-formamide 1 h;
参考文献
Mercader, Josep V.; Agullo, Consuelo; Abad-Somovilla, Antonio; Abad-Fuentes, Antonio
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 5 p. 1443 - 1453
反应条件
in potassium hydroxide
反应条件
in potassium tert-butylate; water; tert-butyl alcohol
反应条件
potassium tert-butylate in tert-butyl alcohol T=0 - 30°C; regioselective reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 19 p. 8211 - 8224,14
反应条件
1.1: ethanol; sodium / toluene / 0.17 h / 40 °C / Inert atmosphere 1.2: 1.83 h / Inert atmosphere 2.1: oxygen; copper(l) chloride / N,N-dimethyl-formamide / 3 h / 20 °C 2.2: 1 h View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 5 p. 1443 - 1453
反应条件
1: With sodium methylate in methanol T=100°C; 2 h; Cooling with ice; 2: With sulfuric acid in methanol; water T=100°C; 2 h;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED; YOSHIMOTO, Yuya; ARIMORI, Sadayuki; MATSUZAKI, Yuichi
Patent: WO2013/162072 A1, 2013 ;
Location in patent: Page/Page column 954 ;
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 0.33 h / Cooling with ice 1.2: 2 h / -10 - -5 °C 2.1: sodium methylate / ethanol; toluene / 16 h / 40 - 45 °C 3.1: FeCl3·6H2O / N,N-dimethyl-formamide / 16 h / 80 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 31, # 11 p. 3341 - 3347
反应条件
potassium carbonate in N,N-dimethyl-formamide T=50°C;
参考文献
BASF SE
Patent: US2013/5986 A1, 2013 ;
Location in patent: Page/Page column 14 ;
