反应条件
1: 10 N aq. NaOH / 0.33 h / 70 °C
2: triethylbenzylammonium chloride, 10 N aq. NaOH / CH2Cl2 / Ambient temperature
3: m-chloroperoxybenzoic acid / CH2Cl2 / Ambient temperature
4: t-Bu0K / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Brown, Thomas J.; Chapman, Robert F.; Cook, David C.; Hart, Terance W.; McLay, Iain M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 20 p. 3613 - 3624