[2-(1-羟基-6-氧代-1,6-二氢-2-吡啶基)乙基]膦酸合成路线 （共 1 条）
反应条件
1: t-Bu4NOAc; potassium chloride; palladium diacetate; potassium carbonate / N,N-dimethyl-formamide / 90 °C
2: palladium 10 on activated carbon; hydrogen / methanol / 20 °C
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C
4: trimethylsilyl bromide; water / dichloromethane / 20 °C
View Scheme
参考文献
Andaloussi, Mounir; Lindh, Martin; Bjoerkelid, Christofer; Suresh, Surisetti; Wieckowska, Anna; Iyer, Harini; Karlen, Anders; Larhed, Mats
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5403 - 5407
