甲基3-氨基-4-(丙基氨基)苯甲酸酯合成路线 （共 4 条）
反应条件
1: With carbon in ethylene glycol dimethyl ether
2 h; Heating / reflux;
2: With hydrazine; palladium 10 on activated carbon in ethylene glycol dimethyl ether
T=30 - 45°C; 10.5 h; Heating / reflux;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/69053 A1, 2007 ;
Location in patent: Page/Page column 28 ;
WO 2007/069053 A1
反应条件
palladium on activated charcoal; hydrogen in acetic acid
T=20°C; P=6000.6 Torr;
参考文献
Brink, Mikael; Dahlen, Anders; Olsson, Thomas; Polla, Magnus; Svensson, Tor
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2261 - 2268
反应条件
1: sulfuric acid
2: acetonitrile / 20 °C
3: zinc; ammonium formate / acetonitrile / 20 °C
View Scheme
参考文献
Chen, Li-Hsun; Chuang, Ying-Sheng; Narhe, Bharat D.; Sun, Chung-Ming
RSC Advances, 2013 , vol. 3, # 33 p. 13934 - 13943
反应条件
1: acetonitrile / 20 °C
2: zinc; ammonium formate / acetonitrile / 20 °C
View Scheme
参考文献
Chen, Li-Hsun; Chuang, Ying-Sheng; Narhe, Bharat D.; Sun, Chung-Ming
RSC Advances, 2013 , vol. 3, # 33 p. 13934 - 13943
