1-叔丁基-1,4-二氢四唑-5-硫酮合成路线 （共 3 条）
反应条件
1: 91 percent / K2CO3 / CH2Cl2 / 48 h / 20 - 25 °C
2: 74 percent / (PhCN)2PdCl2 / benzene / 120 h / 80 °C
View Scheme
参考文献
Quast, Helmut; Nahr, Uwe
Chemische Berichte, 1983 , vol. 116, # 10 p. 3427 - 3437
反应条件
potassium carbonate in dichloromethane
T=20 - 25°C; 48 h;
参考文献
Quast, Helmut; Nahr, Uwe
Chemische Berichte, 1983 , vol. 116, # 10 p. 3427 - 3437
反应条件
1: 1-tert-butyl-1H-tetrazol-5-yl thiol With potassium hydroxide in ethanol
Metallation;
2: allyl bromide in ethanol
Alkylation; 20 h; Heating;
参考文献
Kocienski, Philip J.; Bell, Alan; Blakemore, Paul R.
Synlett, 2000 , # 3 p. 365 - 366
