咪唑并[1,5-a]吡啶-3(2H)-硫酮合成路线 (共 4 条)
反应条件
potassium carbonate in acetone
T=45°C;
参考文献
Blatcher, Philip; Middlemiss, David
Tetrahedron Letters, 1980 , vol. 21, p. 2195 - 2196
反应条件
1: 100 percent / K2CO3 / acetone / 45 °C
2: 1.) BuLi
3: 43 percent / Raney nickel
View Scheme
参考文献
Blatcher, Philip; Middlemiss, David
Tetrahedron Letters, 1980 , vol. 21, p. 2195 - 2196
反应条件
1: 100 percent / K2CO3 / acetone / 45 °C
2: 1.) n-butyl lithium / 1.) THF, -78 deg C; 2.) from -78 deg C to room temperature
3: Raney nickel / ethanol / Heating
View Scheme
参考文献
Blatcher, Philip; Middlemiss, David
Tetrahedron Letters, 1980 , vol. 21, p. 2195 - 2196
参考文献
American Home Products Corporation
Patent: US4419516 A1, 1983 ;