1-(溴甲基)-4-氯-2-甲氧基苯合成路线 （共 3 条）
反应条件
phosphorus tribromide in diethyl ether
T=0°C; 1 h; Inert atmosphere;
参考文献
Marchand, Pascal; Antoine, Maud; Baut, Guillaume Le; Czech, Michael; Baasner, Silke; Guenther, Eckhard
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6715 - 6727
反应条件
N-bromosuccinmide; azobisisobutyronitrile in tetrachloromethane
参考文献
Bayer Aktiengesellschaft
Patent: US6472419 B1, 2002 ;
反应条件
1: 58 percent / diborane / tetrahydrofuran / 1.5 h / 0 °C
2: PBr3 / toluene / 0.17 h / 100 °C
View Scheme
参考文献
Kelley; Linn; Selway
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1757 - 1763
