2,4-二甲基噻吨-9-酮合成路线 （共 6 条）
反应条件
in sodium hydroxide; sulfuric acid; water
参考文献
Solow-Cordero, David; Shankar, Geetha; Spencer, Juliet V.; Gluchowski, Charles
Patent: US2005/261298 A1, 2005 ;
US 20050261298 A1
反应条件
sulfuric acid
1.) 20 h, 2.) heating, 1 h;
参考文献
Okabayashi; Kimura; Fujiwara; Kato
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549
反应条件
sulfuric acid
0.5 h; Heating;
参考文献
Okabayashi; Kimura; Fujiwara; Kato
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549
反应条件
1: 68 percent / copper powder, Na / methanol / 1.) 100 deg C, 2.) 100 deg C to 230 deg C, 20 min, 3.) 230 deg C, 15 min
2: 43 percent / conc. H2SO4 / 0.5 h / Heating
View Scheme
参考文献
Okabayashi; Kimura; Fujiwara; Kato
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549
反应条件
1: 68 percent / copper powder, Na / methanol / 1.) 100 deg C, 2.) 100 deg C to 230 deg C, 20 min, 3.) 230 deg C, 15 min
2: 43 percent / conc. H2SO4 / 0.5 h / Heating
View Scheme
参考文献
Okabayashi; Kimura; Fujiwara; Kato
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549
反应条件
sulfuric acid
1.) 20 h, 2.) heating, 1 h;
参考文献
Okabayashi; Kimura; Fujiwara; Kato
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549
