3-甲基-3-丁烯-1-醇合成路线 （共 220 条）
反应条件
1: BF3*Et2O / tetrahydrofuran / 64 h / Heating 2: 81 percent / DDQ / toluene / 18 h / Heating View Scheme
参考文献
Habonimana, Pascal; Claessens, Sven; De Kimpe, Norbert
Synlett, 2006 , # 15 p. 2472 - 2475
反应条件
Na34[{MoVI6O21(H2O)6}12{(MoV2O4)30(OAc)22(H2O)16}] in water-d2 T=65°C; 65 h;
参考文献
Kopilevich, Sivil; Gil, Adria; Garcia-Rates, Miquel; Bonet-Avalos, Josep; Bo, Carles; Mueller, Achim; Weinstock, Ira A.
Journal of the American Chemical Society, 2012 , vol. 134, # 31 p. 13082 - 13088
反应条件
1.1: triethylamine / toluene / 5 - 20 °C 2.1: sodium ethanolate / ethanol / 60 °C 2.2: 80 °C 3.1: N,N-dioctyl-1-octylamine; water / 160 - 170 °C View Scheme
参考文献
KURARAY CO., LTD.
Patent: US2012/253062 A1, 2012 ;
反应条件
1.1: triethylamine / toluene / 5 - 20 °C 2.1: sodium ethanolate / ethanol / 60 °C 2.2: 80 °C 3.1: water / 160 - 170 °C View Scheme
参考文献
KURARAY CO., LTD.
Patent: US2012/253062 A1, 2012 ;
反应条件
1.1: pyridine / dichloromethane / 15.25 h / 0 - 20 °C / Inert atmosphere 2.1: sodium hydride; potassium iodide / tetrahydrofuran; mineral oil / 0.25 h / 20 - 70 °C / Inert atmosphere 2.2: 20.08 h / 70 °C / Inert atmosphere 3.1: sodium hydroxide / tetrahydrofuran; ethanol; water / 40 h / 20 °C 3.2: 0 °C / pH 3 4.1: copper(I) oxide / acetonitrile / 20 h / 85 °C / Inert atmosphere 4.2: 0 °C / Inert atmosphere View Scheme
参考文献
Ghosh, Arun K.; Nicponski, Daniel R.
Organic Letters, 2011 , vol. 13, # 16 p. 4328 - 4331
反应条件
1: 91 percent / Et3N / CH2Cl2 / 0.25 h / 0 °C 2: 57 percent / LiBr / acetone / 15 h / Heating 3: 1.) Mg, 3.) aq. HCl 4: 1.) t-BuOH, Li, NH3(liquid), 3.) 4percent KOH View Scheme
参考文献
Paquette, Leo A.; Sauer, Daryl R.; Cleary, Darryl G.; Kinsella, Mary A.; Blackwell, Christopher M.; Anderson, Lawrence G.
Journal of the American Chemical Society, 1992 , vol. 114, # 19 p. 7375 - 7387
反应条件
in 1,2,2-trifluoro-trichloroethane T=-196.1°C; Irradiationγ-irradiation in CF3CCl3 at 77 deg K; Mechanism;
参考文献
Dai, Sheng; Wang, Jih Tzong; Williams, Ffrancon
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1063 - 1064
反应条件
1: 200 °C 2: Raney nickel; dioxane / 100 °C / 257428 Torr / Hydrogenation View Scheme
参考文献
Du Pont de Nemours and Co.
Patent: US2789996 , 1953 ;
反应条件
2.1: BH3*THF 2.2: NaOH; H2O2 View Scheme
参考文献
Yan, Jingbo; Herndon, James W.
Journal of Organic Chemistry, 1998 , vol. 63, # 7 p. 2325 - 2331
反应条件
zinc/copper couple in diethyl ether T=40°C;
参考文献
BAYER PHARMA AKTIENGESELLSCHAFT; HAHN, Michael; LAMPE, Thomas; STASCH, Johannes-Peter; SCHLEMMER, Karl-Heinz; WUNDER, Frank; LI, Volkhart Min-Jian; BECKER, Eva-Maria; STOLL, Friederike; KNORR, Andreas; WOLTERING, Elisabeth
Patent: US2013/79412 A1, 2013 ;
Location in patent: Paragraph 0678-0679 ;
